Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 10/20 | 0.67 |
| ▸ | APP | P05067 | 1/20 | 0.57 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.55 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.54 |
| ▸ | SOD1 | P00441 | 1/20 | 0.54 |
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | AGXT | P21549 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13462942 | 0.91 | MAOB (0.69) | MAOBAPPABCB1MRGPRX4SOD1 | |
| SCHEMBL13462938 | 0.88 | MAOB (0.65) | MAOBAPPABCB1BCHE | |
| SCHEMBL10796146 | 0.84 | MAPK1 (0.60) | MAOBAPPIDO1AGXTKDM4E | |
| SCHEMBL29925214 | 0.84 | MAOB (0.68) | MAOBSOD1BCHEKDM4EALDH1A1 | |
| SCHEMBL91188 | 0.84 | MAOB (0.68) | MAOBSOD1BCHEKDM4EALDH1A1 | |
| SCHEMBL12903697 | 0.83 | MAOB (0.47) | MAOBAPPABCB1ALDH1A1 | |
| SCHEMBL29908907 | 0.83 | TAAR1 (0.62) | MAOBIDO1AGXT | |
| SCHEMBL12497 | 0.83 | TAAR1 (0.62) | MAOBIDO1AGXT | |
| SCHEMBL7917111 | 0.83 | MAOB (0.62) | MAOBAPPABCB1MRGPRX4 | |
| SCHEMBL5987976 | 0.83 | MAOB (0.76) | MAOBAPPABCB1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129538-B1 | Renin inhibitors | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |