Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 14/20 | 0.42 |
| ▸ | LY96 | Q9Y6Y9 | 6/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | PGR | P06401 | 1/20 | 0.37 |
| ▸ | HTR1A | P08908 | 1/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | AR | P10275 | 1/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.37 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | CDC25A | P30304 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9124251 | 0.93 | TLR4 (0.38) | TLR4LY96MEN1ALDH1A1HPGD | |
| SCHEMBL9125663 | 0.90 | MEN1 (0.42) | TLR4LY96MEN1ALDH1A1HPGD | |
| SCHEMBL9126725 | 0.87 | TLR4 (0.42) | TLR4LY96ESR1PGRHTR1A | |
| SCHEMBL9126337 | 0.87 | TLR4 (0.42) | TLR4LY96ESR1PGRHTR1A | |
| SCHEMBL9127723 | 0.87 | TLR4 (0.42) | TLR4LY96ESR1PGRHTR1A | |
| SCHEMBL9127473 | 0.87 | TLR4 (0.42) | TLR4LY96ESR1PGRHTR1A | |
| SCHEMBL9128735 | 0.84 | TLR2 (0.42) | TLR4LY96MEN1ALDH1A1HPGD | |
| SCHEMBL9123760 | 0.84 | MEN1 (0.38) | TLR4LY96MEN1ALDH1A1HPGD | |
| SCHEMBL9126181 | 0.83 | MEN1 (0.42) | TLR4LY96MEN1ALDH1A1HPGD | |
| SCHEMBL9125725 | 0.83 | MEN1 (0.42) | TLR4LY96MEN1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432267-A | Inhibits tumor necrosis factor derivation by endotoxin | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1995-07-11 | — | — | US | disclosed |
| EP-0563908-A1 | Amino sugar derivatives | DAIICHI PHARMACEUTICAL CO., LTD. (JP) | 1993-10-06 | — | — | EP | disclosed |