SCHEMBL912841

SCHEMBL912841

Nc1cnc(Cl)cn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6222849 1.00 PIK3CD (0.50)
SCHEMBL21045448 0.86 PIK3CD (0.41)
SCHEMBL647114 0.80
SCHEMBL933680 0.80
Hydrochloric Acid SCHEMBL29354497 0.77 HSP90AA1 (0.47)
SCHEMBL21266740 0.71 PIK3CD (0.66)
SCHEMBL18328361 0.71
SCHEMBL9939593 0.69 PDPK1 (0.52)
SCHEMBL30835316 0.69
Potassium SCHEMBL31605669 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 437 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220402875-A1 S1P3 Antagonists TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2022-12-22 US claimed
EP-3689864-A1 S1P3 ANTAGONISTS Teva Pharmaceutical Industries Limited (IL) 2020-08-05 EP claimed
US-20200157052-A1 S1P3 Antagonists TEVA PHARMACEUTICAL INDUSTRIES, LTD. (IL) 2020-05-21 US claimed
EP-3086845-B1 S1P3 ANTAGONISTS TEVA PHARMACEUTICAL INDUSTRIES LTD (IL) 2019-11-20 EP claimed
US-20180201582-A1 S1P3 ANTAGONISTS TEVA PHARMACEUTICAL INDUSTRIES LIMITED (IL) 2018-07-19 US claimed
US-9951017-B2 S1P3 antagonists TEVA PHARMACEUTICAL INDUSTRIES LIMITED (IL) 2018-04-24 US claimed
CN-106963332-A A kind of endoscope sheath inserting tube 徐州市第人民医院 2017-07-21 CN claimed
CN-106917321-A A kind of mechanics ecological board and mechanics ecology board manufacturing method 西京学院 2017-07-04 CN claimed
CN-106867152-A A kind of sports place track material 景德镇陶瓷大学 2017-06-20 CN claimed
CN-106823243-A A kind of athletic training cushion pad 景德镇陶瓷大学 2017-06-13 CN claimed
CN-106785081-A A kind of battery liquid and its battery 叶晓东 2017-05-31 CN claimed
CN-106674943-A Method for producing disposable tableware through polylactic acid 平凉市佳禾农产品加工有限责任公司 2017-05-17 CN claimed
EP-3086845-A1 S1P3 ANTAGONISTS Teva Pharmaceutical Industries Limited (IL) 2016-11-02 EP claimed
US-20160297762-A1 S1P3 ANTAGONISTS TEVA PHARMACEUTICAL INDUSTRIES LIMITED (IL) 2016-10-13 US claimed
CN-105017569-A Degradable composite tourist commodity packaging film and preparation method thereof JILIN TECHNOLOGY COLLEGE OF ELECTRONIC INFORMATION 2015-11-04 CN claimed
WO-2015082357-A1 S1P3 ANTAGONISTS SIENA BIOTECH S.P.A. (IT) 2015-06-11 WO claimed
EP-2878339-A1 SIP3 antagonists Siena Biotech S.p.A. (IT) 2015-06-03 EP claimed
US-20250376475-A1 ION CHANNEL MODULATORS PRAXIS PREC MEDICINES INC (US) 2025-12-11 US disclosed
US-4133956-A Preparation of benzoylureas ELI LILLY AND COMPANY (US) 1979-01-09 US disclosed
US-4083977-A Novel insecticidal 1-(substituted benzoyl)-3-(substituted pyrazinyl)ureas ELI LILLY AND COMPANY (US) 1978-04-11 US disclosed