Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 2/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | KDM1A | O60341 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11974552 | 0.88 | ELANE (0.72) | ELANEKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL28386407 | 0.85 | ELANE (0.68) | ELANEALDH1A1TDP1RECQLKDM1A | |
| SCHEMBL4061370 | 0.84 | ELANE (0.81) | ELANEKMT2ARAB9AMAPTTDP1 | |
| SCHEMBL10483714 | 0.82 | ELANE (1.00) | ELANEKDM1A | |
| SCHEMBL26802703 | 0.81 | KMT2A (0.58) | ELANEKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL8998586 | 0.81 | ELANE (0.77) | ELANEKMT2ASMN1; SMN2RAB9ANPC1 | |
| SCHEMBL4059722 | 0.81 | ELANE (0.77) | ELANEKMT2ASMN1; SMN2ALDH1A1MAPT | |
| SCHEMBL4060714 | 0.81 | ELANE (0.77) | ELANEKMT2ASMN1; SMN2RAB9AMAPT | |
| SCHEMBL12895341 | 0.80 | ELANE (0.56) | ELANEKMT2ARAB9ANPC1ALDH1A1 | |
| SCHEMBL23802411 | 0.79 | KMT2A (0.53) | ELANEKMT2ASMN1; SMN2RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5470928-A | Free radical copper(II)-enolate polymerization initiators | UNIVERSITY OF AKRON (US) | 1995-11-28 | — | — | US | disclosed |
| US-5405913-A | Telechelic, block and graft polymers | THE UNIVERSITY OF AKRON (US) | 1995-04-11 | — | — | US | disclosed |