Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMPD1 | P17405 | 3/20 | 0.50 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.49 |
| ▸ | LPAR3 | Q9UBY5 | 5/20 | 0.48 |
| ▸ | LPAR1 | Q92633 | 7/20 | 0.47 |
| ▸ | LPAR2 | Q9HBW0 | 3/20 | 0.47 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | LPAR4 | Q99677 | 2/20 | 0.41 |
| ▸ | LPAR5 | Q9H1C0 | 2/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | LPAR6 | P43657 | 1/20 | 0.41 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.41 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | TSPO | P30536 | 1/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4064805 | 1.00 | SMPD1 (0.50) | SMPD1SLC6A5LPAR3LPAR1LPAR2 | |
| SCHEMBL3332099 | 1.00 | SMPD1 (0.50) | SMPD1SLC6A5LPAR3LPAR1LPAR2 | |
| SCHEMBL27542771 | 0.91 | SMPD1 (0.59) | SMPD1PTPN1S1PR1S1PR4S1PR3 | |
| SCHEMBL744377 | 0.91 | SMPD1 (0.59) | SMPD1PTPN1S1PR1S1PR4S1PR3 | |
| SCHEMBL5481597 | 0.91 | SMPD1 (0.59) | SMPD1PTPN1S1PR1S1PR4S1PR3 | |
| SCHEMBL27835477 | 0.91 | SMPD1 (0.59) | SMPD1PTPN1S1PR1S1PR4S1PR3 | |
| SCHEMBL596695 | 0.91 | SMPD1 (0.59) | SMPD1PTPN1S1PR1S1PR4S1PR3 | |
| SCHEMBL1044719 | 0.91 | SMPD1 (0.59) | SMPD1PTPN1S1PR1S1PR4S1PR3 | |
| SCHEMBL27699114 | 0.91 | SMPD1 (0.59) | SMPD1PTPN1S1PR1S1PR4S1PR3 | |
| SCHEMBL9026174 | 0.90 | SMPD1 (0.49) | SMPD1LPAR3LPAR1LPAR2ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5436234-A | Treatment of protozoal and fungal diseases, autoimmune diseases and bone marrow damage | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG (DE) | 1995-07-25 | — | — | US | claimed |
| US-5436234-A | Treatment of protozoal and fungal diseases, autoimmune diseases and bone marrow damage | MAX-PLANCK-GESELLSCHAFT ZUR FORDERUNG (DE) | 1995-07-25 | — | — | US | disclosed |