Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNN4 | O15554 | 4/20 | 0.56 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.36 |
| ▸ | DRD3 | P35462 | 3/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.36 |
| ▸ | DRD2 | P14416 | 2/20 | 0.36 |
| ▸ | DRD4 | P21917 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5921941 | 0.72 | KCNN4 (1.00) | KCNN4OPRM1DRD3CYP2D6DRD2 | |
| SCHEMBL29262765 | 0.69 | KCNN4 (0.64) | KCNN4OPRM1DRD3CYP2D6DRD2 | |
| SCHEMBL10013102 | 0.68 | KCNN4 (0.39) | KCNN4CYP2D6MAPK1KMT2AMAPT | |
| SCHEMBL9130272 | 0.68 | KCNN4 (0.56) | KCNN4OPRM1DRD3CYP2D6DRD2 | |
| SCHEMBL2092051 | 0.67 | KCNN4 (0.48) | KCNN4OPRM1DRD3CYP2D6DRD2 | |
| SCHEMBL2092055 | 0.67 | KCNN4 (0.48) | KCNN4OPRM1DRD3CYP2D6DRD2 | |
| SCHEMBL14857236 | 0.66 | KCNN4 (0.60) | KCNN4MAPK1ALDH1A1CYP3A4TSHR | |
| SCHEMBL10425497 | 0.65 | KCNN4 (0.58) | KCNN4OPRM1DRD3CYP2D6DRD2 | |
| SCHEMBL10483069 | 0.65 | KCNN4 (0.46) | KCNN4CYP2D6MAPK1KMT2AMAPT | |
| SCHEMBL24160487 | 0.64 | KCNN4 (0.56) | KCNN4OPRM1DRD3CYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5455363-A | Having trityl as amide-protecting group for asparagine and glutamine; reduced side reaction | GOSTELI JACQUES (CH) | 1995-10-03 | — | — | US | disclosed |