Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.55 |
| ▸ | HTR1D | P28221 | 9/20 | 0.50 |
| ▸ | HTR1E | P28566 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9128659 | 0.91 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL9128022 | 0.89 | SLC6A4 (0.55) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL9129606 | 0.88 | SLC6A4 (0.61) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL9130378 | 0.85 | SLC6A4 (0.53) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL9128867 | 0.83 | HTR1D (0.55) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL9163972 | 0.83 | HTR1D (0.75) | SLC6A4SLC6A2HTR1DHTR1EHTR1A | |
| SCHEMBL9126825 | 0.83 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL9130185 | 0.82 | HTR1D (0.57) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL9129397 | 0.82 | SLC6A4 (0.66) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E | |
| SCHEMBL8874445 | 0.82 | SLC6A4 (0.52) | SLC6A4SLC6A2SLC6A3HTR1DHTR1E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468767-A | FOR ADMINISTERING TO MAMMALS | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-11-21 | — | — | US | claimed |