Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SNCA | P37840 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LIG1 | P18858 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GABRP | O00591 | 1/20 | 0.35 |
| ▸ | GABRD | O14764 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.35 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9132292 | 0.84 | TSHR (0.48) | TSHRGAAALDH1A1HSD17B10KDM4E | |
| SCHEMBL9131544 | 0.76 | TSHR (0.54) | CYP3A4TSHRGAAMEN1KMT2A | |
| SCHEMBL2215894 | 0.76 | POLB (0.60) | GAAKMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL17544250 | 0.76 | CYP3A4 (0.45) | CYP3A4TSHRGAAMEN1KMT2A | |
| SCHEMBL13690626 | 0.73 | KDM4E (0.57) | CYP3A4TSHRGAAMEN1KMT2A | |
| SCHEMBL8055864 | 0.73 | MEN1 (0.54) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL9131061 | 0.72 | TSHR (0.56) | CYP3A4TSHRGAAALDH1A1HSD17B10 | |
| SCHEMBL2359576 | 0.72 | CYP3A4 (0.47) | CYP3A4TSHRMEN1KMT2AALDH1A1 | |
| SCHEMBL25233675 | 0.71 | CYP3A4 (0.46) | CYP3A4TSHRGAAMEN1KMT2A | |
| SCHEMBL1944089 | 0.71 | TSHR (0.50) | CYP3A4TSHRGAAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5447925-A | Carbapenems with side-chain S; use to treat infections | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1995-09-05 | — | — | US | disclosed |
| EP-0580632-A1 | ANTIBIOTIC CARBAPENEM DERIVATIVES | ZENECA LIMITED (GB) | 1994-02-02 | — | — | EP | disclosed |