Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 11/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9130522 | 1.00 | KDM4E (0.39) | KDM4EALDH1A1LMNACTSLL3MBTL1 | |
| SCHEMBL3070503 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1LMNACTSLL3MBTL1 | |
| SCHEMBL3070506 | 0.92 | KDM4E (0.44) | KDM4EALDH1A1LMNACTSLL3MBTL1 | |
| SCHEMBL4100479 | 0.74 | KMT2A (0.52) | KDM4EALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL27943531 | 0.72 | KMT2A (0.55) | KDM4EALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL941085 | 0.72 | KMT2A (0.55) | KDM4EALDH1A1LMNANPSR1MEN1 | |
| SCHEMBL467998 | 0.72 | KMT2A (0.54) | LMNAL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL13609696 | 0.72 | KMT2A (0.54) | LMNAL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL187817 | 0.72 | KMT2A (0.54) | LMNAL3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL3809677 | 0.69 | TSHR (0.56) | ALDH1A1LMNAL3MBTL1NPSR1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | claimed |
| US-5421897-A | Applying liquid composition to surface contaminated with lead, solidifying into matrix which sequesters lead, removing matrix | GRAWE JOHN (US) | 1995-06-06 | — | — | US | disclosed |