Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NT5E | P21589 | 6/20 | 0.69 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.69 |
| ▸ | PRKCG | P05129 | 2/20 | 0.67 |
| ▸ | CA9 | Q16790 | 1/20 | 0.67 |
| ▸ | CETP | P11597 | 1/20 | 0.67 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12557822 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL13890818 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL10214444 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL14124010 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL9130088 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL9129432 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL10214496 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL14156586 | 1.00 | NT5E (0.69) | NT5EPRKCDPRKCGCA9CETP | |
| SCHEMBL9129051 | 0.93 | GPBAR1 (0.67) | — | |
| SCHEMBL10214539 | 0.93 | NT5E (0.71) | NT5EPRKCDPRKCGCETPPTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5468888-A | Lupane derivatives, their preparation and the pharmaceutical compositions which contain them | RHONE-POULENC RORER S.A. (FR) | 1995-11-21 | — | — | US | disclosed |