⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30925652 | 1.00 | — | — | |
| SCHEMBL9003282 | 1.00 | — | — | |
| Hydrochloric Acid SCHEMBL18047418 | 0.98 | — | — | |
| Hydrochloric Acid SCHEMBL18047416 | 0.98 | — | — | |
| Trifluoroacetic Acid SCHEMBL29728619 | 0.86 | GABRR1 (0.43) | — | |
| SCHEMBL27439377 | 0.81 | — | — | |
| Hydrochloric Acid SCHEMBL31127727 | 0.79 | HCAR2 (0.50) | — | |
| SCHEMBL3144798 | 0.77 | — | — | |
| SCHEMBL690353 | 0.77 | — | — | |
| SCHEMBL10054177 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 51 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2702035-B1 | PROCESS FOR CONTINUOUS FLOW SYNTHESIS OF BETA-AMINO CROTONATE | COUNCIL SCIENT IND RES (IN) | 2018-03-07 | — | — | EP | claimed |
| US-9199913-B2 | Process for continous flow synthesis of beta-amino crotonate | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2015-12-01 | — | — | US | claimed |
| EP-2702035-A2 | PROCESS FOR CONTINUOUS FLOW SYNTHESIS OF BETA-AMINO CROTONATE | Council of Scientific & Industrial Research (IN) | 2014-03-05 | — | — | EP | claimed |
| US-20140046090-A1 | PROCESS FOR CONTINOUS FLOW SYNTHESIS OF beta-AMINO CROTONATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2014-02-13 | — | — | US | claimed |
| WO-2012147103-A2 | PROCESS FOR CONTINUOUS FLOW SYNTHESIS OF β-ΑΜΙΝΟ CROTONATE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2012-11-01 | — | — | WO | claimed |
| US-6784297-B2 | CONDENSING PHTHALIC ANHYDRIDE AND ETHANOLAMINE, COUPLING WITH ETHYL 4-CHLORACETOACETATE/O-CHLOROBENZALDEHYDE, CONDENSING (CYCLIZATION) WITH METHYL AMINOCROTONATE, PURIFYING, HYDROLYZING, SALT FORMING; COMMERCIALLY VIABLE; EFFICIENCY | KOPRAN LIMITED (IN) | 2004-08-31 | — | — | US | claimed |
| CN-110248934-B | Heteroaryl PAD4 inhibitors | 帕德罗科治疗公司 | 2022-05-24 | — | — | CN | disclosed |
| US-11046762-B2 | Cross-linkers and their uses | IMMUNOGEN, INC. (US) | 2021-06-29 | — | — | US | disclosed |
| EP-3145944-B1 | MACROCYCLIC BROAD SPECTRUM ANTIBIOTICS | RQX PHARMACEUTICALS INC (US) | 2021-05-05 | — | — | EP | disclosed |
| US-20200148764-A1 | CROSS-LINKERS AND THEIR USES | IMMUNOGEN, INC. | 2020-05-14 | — | — | US | disclosed |
| US-20190292167-A1 | HETEROAROMATIC COMPOUNDS USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | SYROS PHARMACEUTICALS INC (US) | 2019-09-26 | — | — | US | disclosed |
| US-10273208-B2 | Screening methods for the binding affinity of chemical entities to biological molecules and NEDD4-1 inhibitors identified by the screening methods | NORTHWESTERN UNIVERSITY (US) | 2019-04-30 | — | — | US | disclosed |
| US-10273208-B2 | Screening methods for the binding affinity of chemical entities to biological molecules and NEDD4-1 inhibitors identified by the screening methods | NORTHWESTERN UNIVERSITY (US) | 2019-04-30 | — | — | US | disclosed |
| US-20040044218-A1 | Reacting phthalic anhydride with ethanolamine | KOPRAN LIMITED (IN) | 2004-03-04 | — | — | US | disclosed |
| US-5430059-A | Treating heart disease | EISAI CO., LTD. (JP) | 1995-07-04 | — | — | US | disclosed |
| EP-0633248-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1995-01-11 | — | — | EP | disclosed |
| EP-0589491-A1 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1994-03-30 | — | — | EP | disclosed |
| US-5292770-A | Butenoic acid derivatives | EISAI CO., LTD. (JP) | 1994-03-08 | — | — | US | disclosed |
| US-5166188-A | Cardiovascular disorders, antiischemic agents | EISAI CO., LTD. (JP) | 1992-11-24 | — | — | US | disclosed |
| EP-0399358-A2 | Butenoic acid derivatives | Eisai Co., Ltd. (JP) | 1990-11-28 | — | — | EP | disclosed |