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SCHEMBL9136259

SCHEMBL9136259

CC(C)c1cccc(C(C)C)c1NC(=O)CSCCCCCCBr

nearest known ligand 0.52

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ MEN1 O00255 1/20 0.46
▸ KMT2A Q03164 1/20 0.46
▸ TDP1 Q9NUW8 1/20 0.46
▸ SOAT1 P35610 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9137522 1.00 SMN1; SMN2 (0.52) SMN1; SMN2MEN1KMT2ATDP1SOAT1
SCHEMBL9137012 1.00 SMN1; SMN2 (0.52) SMN1; SMN2MEN1KMT2ATDP1SOAT1
SCHEMBL282144 0.88 SOAT1 (0.54) SMN1; SMN2SOAT1
SCHEMBL9050595 0.88 SOAT1 (0.54) SMN1; SMN2SOAT1
SCHEMBL9048615 0.88 SOAT1 (0.54) SMN1; SMN2SOAT1
SCHEMBL9048730 0.88 SOAT1 (0.54) SMN1; SMN2SOAT1
SCHEMBL6941060 0.88 SOAT1 (0.54) SMN1; SMN2SOAT1
SCHEMBL9049272 0.88 SOAT1 (0.54) SMN1; SMN2SOAT1
SCHEMBL9050107 0.88 SOAT1 (0.54) SMN1; SMN2SOAT1
SCHEMBL9136794 0.87 SMN1; SMN2 (0.59) SMN1; SMN2MEN1KMT2ATDP1SOAT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5416212-A Antilipemic agents, enzyme inhibitors and anticholesterol agents TAISHO PHARMACEUTICAL CO., LTD. (JP) 1995-05-16 — — US disclosed
EP-0619312-A1 ANILIDE DERIVATIVE TAISHO PHARMACEUTICAL CO. LTD (JP) 1994-10-12 — — EP disclosed