Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.47 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.47 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 2/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.40 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28003608 | 0.83 | CYP19A1 (0.42) | RAB9AMAPTESR1CYP19A1ESR2 | |
| SCHEMBL9419326 | 0.81 | MAPT (0.54) | RAB9AMAPTTDP1MEN1KMT2A | |
| SCHEMBL3995569 | 0.81 | ESR1 (0.55) | RAB9AMAPTESR1CYP19A1ESR2 | |
| SCHEMBL12378828 | 0.81 | MEN1 (0.52) | RAB9AMAPTMEN1LMNAKMT2A | |
| SCHEMBL1312570 | 0.81 | MAPT (0.55) | RAB9AMAPTESR1CYP19A1ESR2 | |
| Hydrochloric Acid SCHEMBL11148769 | 0.81 | MAPT (0.55) | RAB9AMAPTESR1CYP19A1ESR2 | |
| Hydrochloric Acid SCHEMBL7148684 | 0.81 | MAPT (0.55) | RAB9AMAPTESR1CYP19A1ESR2 | |
| SCHEMBL4582345 | 0.81 | MAPT (0.54) | RAB9AMAPTTDP1MEN1LMNA | |
| SCHEMBL8487007 | 0.80 | CA12 (0.46) | RAB9AMAPTESR1CYP19A1ESR2 | |
| SCHEMBL13773412 | 0.80 | CA12 (0.49) | RAB9AMAPTTDP1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1773768-B1 | PYRROLE DERIVATIVES AS PHARMACEUTICAL AGENTS | EXELIXIS INC (US) | 2018-08-22 | — | — | EP | disclosed |
| US-5453501-A | Phthalocyanine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1995-09-26 | — | — | US | disclosed |
| EP-0582886-A1 | Phthalocyanine reactive dyes | BAYER AG (DE) | 1994-02-16 | — | — | EP | disclosed |
| EP-0038453-B1 | PROCESS FOR THE PREPARATION OF WATER SOLUBLE PHTHALOCYANINE DYESTUFFS | BAYER AG (DE) | 1983-05-25 | — | — | EP | disclosed |
| EP-0012349-B1 | PROCESS FOR PRODUCING PHTHALOCYANINE REACTIVE DYESTUFFS | BAYER AG (DE) | 1981-11-04 | — | — | EP | disclosed |
| EP-0038453-A2 | Process for the preparation of water soluble phthalocyanine dyestuffs | BAYER AG (DE) | 1981-10-28 | — | — | EP | disclosed |
| US-4246174-A | Process for the preparation of phthalocyanine reactive dyestuffs | BAYER AKTIENGESELLSCHAFT (DE) | 1981-01-20 | — | — | US | disclosed |
| EP-0012349-A2 | Process for producing phthalocyanine reactive dyestuffs | BAYER AG (DE) | 1980-06-25 | — | — | EP | disclosed |