Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 4/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.47 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.46 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 2/20 | 0.41 |
| ▸ | LTA4H | P09960 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7138720 | 0.89 | S1PR1 (0.47) | S1PR1S1PR3FFAR1S1PR5 | |
| SCHEMBL9136646 | 0.88 | FFAR1 (0.48) | S1PR1S1PR3FFAR1MMP9LTA4H | |
| SCHEMBL9133024 | 0.85 | FFAR1 (0.52) | S1PR1S1PR3FFAR1MMP9LTA4H | |
| SCHEMBL9129123 | 0.79 | FFAR1 (0.51) | FFAR1MMP9LTA4HMMP8HDAC8 | |
| SCHEMBL7441580 | 0.79 | FFAR1 (0.51) | FFAR1MMP9LTA4HMMP8HDAC8 | |
| SCHEMBL7138716 | 0.78 | FFAR1 (0.49) | S1PR1S1PR3FFAR1 | |
| SCHEMBL8635245 | 0.78 | MAOB (0.54) | — | |
| SCHEMBL8637844 | 0.77 | SCN9A (0.54) | — | |
| SCHEMBL9132534 | 0.75 | HRH3 (0.57) | FFAR1 | |
| SCHEMBL24041893 | 0.75 | FFAR1 (0.57) | S1PR1S1PR3FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5446066-A | Antiepileptic, antidepressants, antispastic agent | FARMITALIA CARLO ERBA S.R.L. (IT) | 1995-08-29 | — | — | US | disclosed |