Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 2/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.32 |
| ▸ | USP5 | P45974 | 2/20 | 0.32 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.31 |
| ▸ | HTR2C | P28335 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.31 |
| ▸ | HCRTR2 | O43614 | 2/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138202 | 1.00 | ESR2 (0.33) | ESR2CCR2USP5HDAC6CYP2C9 | |
| SCHEMBL9312054 | 0.96 | ESR2 (0.35) | ESR2CCR2USP5HDAC6CYP2C9 | |
| SCHEMBL9312059 | 0.96 | ESR2 (0.35) | ESR2CCR2USP5HDAC6CYP2C9 | |
| SCHEMBL8517428 | 0.96 | ESR2 (0.35) | ESR2CCR2USP5HDAC6CYP2C9 | |
| SCHEMBL8517430 | 0.96 | ESR2 (0.35) | ESR2CCR2USP5HDAC6CYP2C9 | |
| SCHEMBL8517429 | 0.96 | ESR2 (0.35) | ESR2CCR2USP5HDAC6CYP2C9 | |
| SCHEMBL10027426 | 0.92 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL9166201 | 0.92 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8633516 | 0.92 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B | |
| SCHEMBL8633522 | 0.92 | USP5 (0.33) | USP5HDAC6HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478497-A | For electro-optical purposes | HOFFMANN-LA ROCHE INC. (US) | 1995-12-26 | — | — | US | disclosed |