SCHEMBL9138262

SCHEMBL9138262

CC(C)=CCC/C(C)=C/CC/C(C)=C/CCC=O

nearest known ligand 0.77

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 3/20 0.77
SQLE Q14534 7/20 0.65
MAPT P10636 2/20 0.61
ALDH1A1 P00352 2/20 0.61
MEN1 O00255 2/20 0.61
CYP3A4 P08684 2/20 0.61
ALOX15 P16050 2/20 0.61
UGT1A1 P22309 1/20 0.61
KDM4E B2RXH2 1/20 0.55
FNTA P49354 1/20 0.55
FNTB P49356 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1771234 1.00 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL9137864 1.00 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL228928 1.00 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL228929 1.00 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL24092723 0.95 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL9159020 0.95 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL18705403 0.95 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL9159032 0.95 KMT2A (0.77) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL9189400 0.90 KMT2A (0.68) KMT2ASQLEMAPTALDH1A1MEN1
SCHEMBL9189396 0.90 KMT2A (0.68) KMT2ASQLEMAPTALDH1A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114181848-A Bacillus acidocaldarius capable of generating fruity flavor of cream and application thereof 天津科技大学 2022-03-15 CN claimed
US-12064239-B2 Device and methods for detection and monitoring of tuberculosis TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2024-08-20 US disclosed
CN-114181848-B Bacillus acidophilus capable of generating cream fruity flavor and application thereof 天津科技大学 2024-07-16 CN disclosed
CN-114181848-A Bacillus acidocaldarius capable of generating fruity flavor of cream and application thereof 天津科技大学 2022-03-15 CN disclosed
US-20210282678-A1 DEVICE AND METHODS FOR DETECTION AND MONITORING OF TUBERCULOSIS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LIMITED (IL) 2021-09-16 US disclosed
CN-113167695-A Device for collecting volatile organic compounds 法国由内政部代表 2021-07-23 CN disclosed
EP-3602044-A1 DEVICE AND METHODS FOR DETECTION AND MONITORING OF TUBERCULOSIS Technion Research & Development Foundation Limited (IL) 2020-02-05 EP disclosed
WO-2018173060-A1 DEVICE AND METHODS FOR DETECTION AND MONITORING OF TUBERCULOSIS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2018-09-27 WO disclosed
US-9657313-B2 Isoprene oligomer, polyisoprene, processes for producing these materials, rubber composition, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-05-23 US disclosed
US-9657313-B2 Isoprene oligomer, polyisoprene, processes for producing these materials, rubber composition, and pneumatic tire SUMITOMO RUBBER INDUSTRIES, LTD. (JP) 2017-05-23 US disclosed
WO-2012008298-A1 ISOPRENE OLIGOMER, POLYISOPRENE, PROCESSES FOR PRODUCING THESE MATERIALS, RUBBER COMPOSITION, AND PNEUMATIC TIRE 住友ゴム工業株式会社 (JP) 2012-01-19 WO disclosed
EP-0521103-B1 NOVEL CYCLOPROPYL SQUALENE DERIVATIVES AND THEIR USE AS INHIBITORS OF CHOLESTEROL SYNTHESIS MERRELL DOW PHARMA (US) 1995-09-27 EP disclosed
US-5393776-A Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia BRISTOL-MYERS SQUIBB COMPANY (US) 1995-02-28 US disclosed
EP-0571928-A1 Acyclic Tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia Bristol-Myers Squibb Company (US) 1993-12-01 EP disclosed
EP-0521103-A4 NOVEL CYCLOPROPYL SQUALENE DERIVATIVES AND THEIR USE AS INHIBITORS OF CHOLESTEROL SYNTHESIS 1993-03-10 EP disclosed
EP-0521103-A1 NOVEL CYCLOPROPYL SQUALENE DERIVATIVES AND THEIR USE AS INHIBITORS OF CHOLESTEROL SYNTHESIS. MERRELL DOW PHARMA (US) 1993-01-07 EP disclosed
US-5102915-A Cyclopropyl squalene derivatives and their use as inhibitors of cholesterol synthesis MERRELL DOW PHARMACEUTICALS INC. (US) 1992-04-07 US disclosed
EP-0476493-A1 Acyclic tocotrienol analogs in the treatment of hypercholesterolemia and hyperlipidemia Bristol-Myers Squibb Company (US) 1992-03-25 EP disclosed
WO-1991014668-A1 NOVEL CYCLOPROPYL SQUALENE DERIVATIVES AND THEIR USE AS INHIBITORS OF CHOLESTEROL SYNTHESIS MERRELL DOW PHARMACEUTICALS INC. (US) 1991-10-03 WO disclosed
US-5051534-A For treatment of vascular disease MERRELL DOW PHARMACEUTICALS INC. (US) 1991-09-24 US disclosed