Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GGPS1 | O95749 | 6/20 | 0.43 |
| ▸ | FNTA | P49354 | 4/20 | 0.42 |
| ▸ | PGGT1B | P53609 | 3/20 | 0.42 |
| ▸ | FNTB | P49356 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8771615 | 0.87 | GGPS1 (0.44) | GGPS1FNTAPGGT1B | |
| SCHEMBL8771616 | 0.87 | GGPS1 (0.44) | GGPS1FNTAPGGT1B | |
| SCHEMBL8771620 | 0.85 | GGPS1 (0.52) | GGPS1FNTAFNTB | |
| SCHEMBL9137420 | 0.80 | GGPS1 (0.52) | GGPS1FNTAFNTB | |
| SCHEMBL9390313 | 0.80 | GGPS1 (0.43) | GGPS1FNTAPGGT1BFNTB | |
| SCHEMBL8771669 | 0.78 | GGPS1 (0.47) | GGPS1 | |
| SCHEMBL8771593 | 0.77 | GGPS1 (0.55) | GGPS1 | |
| SCHEMBL8771599 | 0.77 | GGPS1 (0.55) | GGPS1 | |
| SCHEMBL8771631 | 0.75 | KMT2A (0.41) | GGPS1FNTAPGGT1BFNTB | |
| SCHEMBL8771655 | 0.75 | GGPS1 (0.49) | GGPS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463181-A | Farnesyl: protein transferase inhibitors as anticancer agents | MERRELL DOW PHARMACEUTICALS INC. (US) | 1995-10-31 | — | — | US | disclosed |