Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | SHBG | P04278 | 2/20 | 0.55 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PGR | P06401 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.50 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.50 |
| ▸ | AR | P10275 | 2/20 | 0.47 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9138309 | 1.00 | CYP19A1 (0.55) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9136998 | 0.84 | SERPINA6 (0.52) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9136995 | 0.84 | SERPINA6 (0.52) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9141227 | 0.83 | SERPINA6 (0.37) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9141220 | 0.83 | SERPINA6 (0.37) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9141189 | 0.79 | CYP19A1 (0.44) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9138437 | 0.79 | SERPINA6 (0.59) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9139911 | 0.77 | CYP19A1 (0.57) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL9139913 | 0.77 | CYP19A1 (0.57) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 | |
| SCHEMBL29754939 | 0.76 | CYP19A1 (0.66) | CYP19A1SERPINA6ALDH1A1SHBGSLC22A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5478862-A | Having progestational activity with minimum ancillary hormonal activity; antiovulation agents | SRI INTERNATIONAL (US) | 1995-12-26 | — | — | US | disclosed |
| EP-0500899-B1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | STANFORD RES INST INT (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5321044-A | Ovulation suppression | SRI INTERNATIONAL (US) | 1994-06-14 | — | — | US | disclosed |
| EP-0500899-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS. | STANFORD RES INST INT (US) | 1992-09-02 | — | — | EP | disclosed |
| US-5116865-A | Antifertility Agents | SRI INTERNATIONAL, A CORP OF CA | 1992-05-26 | — | — | US | disclosed |
| WO-1992004309-A1 | NOVEL 15,16-SECO-19-NOR PROGESTINS | SRI INTERNATIONAL (US) | 1992-03-19 | — | — | WO | disclosed |