Methacrylic Acid

Methacrylic Acid

SCHEMBL9138342

C=C(C)C(=O)O.C=C(C)C(=O)O.CCCCN(OCCO)OCCO

nearest known ligand 0.39

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Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.39
ACHE P22303 1/20 0.34
ALDH1A1 P00352 1/20 0.33
CA12 O43570 2/20 0.32
CA1 P00915 2/20 0.32
CA9 Q16790 2/20 0.32
MEN1 O00255 1/20 0.32
THRB P10828 1/20 0.32
HTT P42858 1/20 0.32
KMT2A Q03164 1/20 0.32
MAPT P10636 1/20 0.32
CES2 O00748 1/20 0.30
HPGD P15428 1/20 0.30
MMP1 P03956 1/20 0.30
MMP2 P08253 1/20 0.30
MMP3 P08254 1/20 0.30
MMP8 P22894 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Methacrylic Acid SCHEMBL9222629 0.90 TSHR (0.33) TSHRTHRB
Pyruvate SCHEMBL1132233 0.90 TSHR (0.36) TSHRACHEALDH1A1CA12CA1
Oxalic Acid SCHEMBL1131170 0.90 TSHR (0.39) TSHRACHEALDH1A1CA12CA1
Acetic Acid SCHEMBL1131179 0.90 TSHR (0.39) TSHRACHEALDH1A1CA12CA1
Bicarbonate SCHEMBL1131249 0.88 TSHR (0.40) TSHRACHEALDH1A1CA12CA1
Glycolic Acid SCHEMBL1131485 0.84 TSHR (0.38) TSHRACHEALDH1A1CA12CA1
Propionic Acid SCHEMBL1131227 0.84 TSHR (0.38) TSHRACHEALDH1A1CA12CA1
SCHEMBL43803 0.84 TSHR (0.46) TSHRACHEALDH1A1CA12CA1
Succinic Acid SCHEMBL1132248 0.83 AKR1B1 (0.42) TSHRALDH1A1MEN1KMT2A
Acetic Acid SCHEMBL8656682 0.83 MEN1 (0.41) TSHRALDH1A1MEN1THRBHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5399460-A Aminoacrylated polyimide E. I. DU PONT DE NEMOURS AND COMPANY (US) 1995-03-21 US disclosed
WO-1995004305-A1 PHOTOSENSITIVE FLUORINATED POLY(AMIC ACID) AMINOACRYLATE SALT E.I. DU PONT DE NEMOURS AND COMPANY (US) 1995-02-09 WO disclosed