Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 8/20 | 0.69 |
| ▸ | MEN1 | O00255 | 3/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.55 |
| ▸ | NPC1 | O15118 | 2/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8867996 | 0.97 | P4HTM (0.70) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9139923 | 0.92 | P4HTM (0.60) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL9139633 | 0.92 | P4HTM (0.60) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9140540 | 0.92 | P4HTM (0.60) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9141303 | 0.92 | P4HTM (0.60) | P4HTMNPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL8867818 | 0.92 | P4HTM (0.57) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9140538 | 0.91 | P4HTM (0.67) | P4HTMNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL9140074 | 0.90 | P4HTM (0.55) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL8868411 | 0.90 | P4HTM (0.55) | P4HTMMEN1KMT2ANPC1RAB9A | |
| SCHEMBL9137816 | 0.90 | P4HTM (0.66) | P4HTMNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |
| CN-1076691-A | Sulfonamido-and sulfonamidocarbonyl-pyridine-2-carboxamides and their pyridine-N-oxides | HOECHST AG (DE) | 1993-09-29 | — | — | CN | disclosed |