Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9142222 | 0.87 | MEN1 (0.30) | — | |
| SCHEMBL9138051 | 0.80 | — | — | |
| SCHEMBL9138532 | 0.77 | KDM4E (0.31) | KDM4E | |
| SCHEMBL9140226 | 0.64 | CDK4 (0.32) | — | |
| SCHEMBL6279059 | 0.64 | — | — | |
| SCHEMBL9137869 | 0.62 | PDK2 (0.33) | — | |
| SCHEMBL9141387 | 0.62 | BACE1 (0.33) | TSHRKDM4EALDH1A1 | |
| SCHEMBL9138065 | 0.62 | CDK4 (0.33) | ALDH1A1 | |
| SCHEMBL9141509 | 0.61 | — | — | |
| SCHEMBL9140326 | 0.61 | PLAT (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5475114-A | Angiotensin-11 antagonist; therapeutical agent used for treating hypertension and chronic heart failure | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1995-12-12 | — | — | US | disclosed |
| EP-0646584-A1 | PYRAZOLOTRIAZOLE DERIVATIVE | YAMANOUCHI PHARMACEUTICAL CO. LTD. (JP) | 1995-04-05 | — | — | EP | disclosed |