Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P4HTM | Q9NXG6 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.49 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9139197 | 0.93 | POLB (0.50) | P4HTMPOLBTDP1MEN1KMT2A | |
| SCHEMBL8869612 | 0.92 | MEN1 (0.49) | P4HTMPOLBTDP1MEN1KMT2A | |
| SCHEMBL8868995 | 0.92 | POLB (0.49) | P4HTMPOLBTDP1MEN1KMT2A | |
| SCHEMBL9140037 | 0.91 | P4HTM (0.60) | P4HTMPOLBTDP1MEN1KMT2A | |
| SCHEMBL9139910 | 0.91 | POLB (0.48) | P4HTMPOLBTDP1MEN1KMT2A | |
| SCHEMBL8868916 | 0.90 | POLB (0.47) | P4HTMPOLBTDP1MEN1KMT2A | |
| SCHEMBL9139908 | 0.89 | MEN1 (0.47) | P4HTMPOLBTDP1MEN1KMT2A | |
| SCHEMBL9018163 | 0.86 | POLB (0.49) | POLBTDP1MEN1KMT2AMAPT | |
| SCHEMBL9138339 | 0.85 | P4HTM (0.65) | P4HTMPOLBMEN1KMT2ARAB9A | |
| SCHEMBL9139775 | 0.85 | P4HTM (0.61) | P4HTMMEN1KMT2AMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5428046-A | Antifibrotic agents | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-06-27 | — | — | US | disclosed |