Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 5/20 | 0.43 |
| ▸ | GFER | P55789 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | MIF | P14174 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 5/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | CASP6 | P55212 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 3/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.39 |
| ▸ | NSD2 | O96028 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9141525 | 0.85 | GAA (0.46) | GAAGFERKMT2AMEN1MIF | |
| SCHEMBL14395147 | 0.84 | PIK3CG (0.54) | PDE10AKMT2AMEN1RAB9ANPC1 | |
| SCHEMBL9145193 | 0.82 | GAA (0.43) | GAAGFERKMT2AMEN1MIF | |
| SCHEMBL9143480 | 0.82 | GAA (0.43) | GAAGFERKMT2AMEN1MIF | |
| SCHEMBL312516 | 0.81 | PDE10A (0.64) | PDE10ARAB9ANPC1PIK3CGMAPT | |
| SCHEMBL6031252 | 0.79 | TP53 (0.45) | GAAGFERKMT2AMEN1MIF | |
| SCHEMBL13778098 | 0.79 | PDE10A (0.56) | PDE10ARAB9ANPC1PIK3CGCCNE1 | |
| SCHEMBL5460421 | 0.78 | PDE10A (0.59) | PDE10AGAAKMT2AMEN1RAB9A | |
| SCHEMBL13304943 | 0.77 | PDE10A (0.53) | PDE10APIK3CGCCNE1CDK2RAD52 | |
| SCHEMBL12953206 | 0.76 | KDM4E (0.54) | PDE10AKMT2AMEN1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5438052-A | Cephalosporin derivatives | HOFFMANN-LA ROCHE INC. (US) | 1995-08-01 | — | — | US | disclosed |
| EP-0544166-A2 | Cephalosporinderivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1993-06-02 | — | — | EP | disclosed |