Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.37 |
| ▸ | FAAH | O00519 | 1/20 | 0.37 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147212 | 0.91 | TSHR (0.48) | TSHRUSP2MAPTALDH1A1HSD17B10 | |
| SCHEMBL9141752 | 0.91 | TSHR (0.48) | TSHRUSP2MAPTALDH1A1HSD17B10 | |
| SCHEMBL9576640 | 0.89 | TSHR (0.50) | TSHRUSP2MAPTALDH1A1HSD17B10 | |
| SCHEMBL9143128 | 0.88 | TSHR (0.50) | TSHRALDH1A1HSD17B10KMT2ASRD5A2 | |
| SCHEMBL9578567 | 0.84 | KMT2A (0.53) | TSHRALDH1A1HSD17B10KMT2ASRD5A2 | |
| SCHEMBL9745977 | 0.81 | KMT2A (0.53) | TSHRALDH1A1HSD17B10KMT2ASRD5A2 | |
| SCHEMBL9141579 | 0.81 | TSHR (0.40) | TSHRUSP2MAPTALDH1A1KMT2A | |
| SCHEMBL9146395 | 0.81 | TSHR (0.40) | TSHRUSP2MAPTALDH1A1KMT2A | |
| SCHEMBL9578560 | 0.80 | TSHR (0.60) | TSHRALDH1A1HSD17B10KMT2ASRD5A2 | |
| SCHEMBL9143135 | 0.78 | TSHR (0.78) | TSHRUSP2MAPTALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5399701-A | Polyfluoroalkyloxypyridinecarboxylic acid and -carboxaldehyde intermediates | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1995-03-21 | — | — | US | disclosed |
| US-5254747-A | Fluorine-containing chiral smectic liquid crystals | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1993-10-19 | — | — | US | disclosed |
| US-5082587-A | ACHIRAL FLUORINE-CONTAINING LIQUID CRYSTALS | 3M INNOVATIVE PROPERTIES COMPANY | 1992-01-21 | — | — | US | disclosed |