Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | IDO1 | P14902 | 3/20 | 0.47 |
| ▸ | CA12 | O43570 | 7/20 | 0.47 |
| ▸ | CA1 | P00915 | 7/20 | 0.47 |
| ▸ | CA2 | P00918 | 7/20 | 0.47 |
| ▸ | CA9 | Q16790 | 7/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30206955 | 0.91 | TDP1 (0.55) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL27610884 | 0.90 | CA12 (0.55) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL28903507 | 0.86 | TDP1 (0.53) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL21423490 | 0.83 | TDP1 (0.47) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL6937740 | 0.81 | CA12 (0.62) | TDP1IDO1CA12CA1CA2 | |
| Pyridine SCHEMBL6937415 | 0.79 | CA12 (0.44) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL2279724 | 0.79 | TDP1 (0.53) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL8274545 | 0.79 | IDO1 (0.55) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL11888006 | 0.79 | TDP1 (0.53) | TDP1IDO1CA12CA1CA2 | |
| SCHEMBL3655190 | 0.79 | MEN1 (0.47) | TDP1IDO1CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5389626-A | 3-aryloxmethyl-cephalosporin derivatives, and their medical use | SANKYO COMPANY, LIMITED (JP) | 1995-02-14 | — | — | US | disclosed |