Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.40 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.40 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.36 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11163715 | 0.93 | CSNK2A2 (0.41) | CSNK2A2CSNK2BCSNK2A1BCL2BCL2L1 | |
| SCHEMBL10903433 | 0.81 | CHRM1 (0.39) | TSHRPOLBKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL10905876 | 0.79 | HSD17B10 (0.40) | POLBKDM4EALDH1A1HSP90AA1RXFP1 | |
| SCHEMBL10998660 | 0.78 | TSHR (0.39) | CSNK2A2CSNK2BCSNK2A1BCL2BCL2L1 | |
| SCHEMBL9031451 | 0.78 | CSNK2A2 (0.40) | CSNK2A2CSNK2BCSNK2A1BCL2BCL2L1 | |
| SCHEMBL11163211 | 0.78 | KDM4E (0.47) | POLBKMT2AMEN1KDM4EALDH1A1 | |
| SCHEMBL10940721 | 0.78 | KDM4E (0.44) | TSHRPOLBKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL10998820 | 0.77 | KDM4E (0.55) | CSNK2A2CSNK2BCSNK2A1POLBKMT2A | |
| Hydrochloric Acid SCHEMBL11160600 | 0.77 | KDM4E (0.45) | TSHRPOLBKDM4EALDH1A1HSP90AA1 | |
| SCHEMBL11175761 | 0.77 | KDM4E (0.33) | TSHRPOLBKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457104-A | Antibacterials | BAYER AKTIENGESELLSCHAFT (DE) | 1995-10-10 | — | — | US | disclosed |
| US-4416884-A | ANTIBIOTIC, BACTERICIDE | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1983-11-22 | — | — | US | disclosed |
| US-4317820-A | β-Lactam series compound and antibacterial pharmaceutical composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1982-03-02 | — | — | US | disclosed |