SCHEMBL9147251

SCHEMBL9147251

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nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 1/20 0.30
MPI P34949 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1547638 0.87 AKR1B1 (0.37) AKR1B1MPI
SCHEMBL23072256 0.87 AKR1B1 (0.37) AKR1B1MPI
SCHEMBL31611656 0.87 AKR1B1 (0.37) AKR1B1MPI
SCHEMBL3857933 0.87 AKR1B1 (0.37) AKR1B1MPI
SCHEMBL12396667 0.79 AKR1B1 (0.37) AKR1B1MPI
SCHEMBL21598343 0.75 AKR1B1 (0.30) AKR1B1MPI
SCHEMBL15329241 0.75 AKR1B1 (0.30) AKR1B1MPI
L-Fucose SCHEMBL29436064 0.75
SCHEMBL8150550 0.75
L-Fucose SCHEMBL466429 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0188749-A2 Derivatives of fumaric acid, process for their preparation and pharmaceutical compositions containing them Speiser, Peter Paul, Prof. Dr. (CH) 1986-07-30 EP claimed
US-5451667-A SPORICIDES, MICROBIOCIDES SPEISER PETER P (CH) 1995-09-19 US disclosed
US-4851439-A TREATMENT OF PSORIASIS SPEISER PETER P (CH) 1989-07-25 US disclosed
EP-0188749-A2 Derivatives of fumaric acid, process for their preparation and pharmaceutical compositions containing them Speiser, Peter Paul, Prof. Dr. (CH) 1986-07-30 EP disclosed