SCHEMBL9147396

SCHEMBL9147396

CCCCCCOC(=O)Nc1cc(C)cc(C(=O)O)c1O

nearest known ligand 0.50

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PLK1 P53350 13/20 0.50
ESR1 P03372 1/20 0.45
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
HPGD P15428 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2C19 P33261 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
PLK3 Q9H4B4 2/20 0.44
EPHX1 P07099 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12846670 0.86 ESR1 (0.47) ESR1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL4839353 0.85 PLK1 (0.67) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL1592862 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL1345242 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL1592319 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL8652946 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL1592343 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL1592315 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL1592347 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1
SCHEMBL1592759 0.81 SMN1; SMN2 (0.57) PLK1KDM4EALDH1A1HPGDL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5476957-A Dye for heat sensitive recording MITSUI TOATSU CHEMICALS, INC. (JP) 1995-12-19 US disclosed
US-5346878-A Preservation stability of white portions and images MITSUI TOATSU CHEMICALS, INC. (JP) 1994-09-13 US disclosed
US-5306688-A Color-forming, electron donating compound and electron accepting compound; storage stability of uncolored portion MITSUI TOATSU CHEMICALS, INC. (JP) 1994-04-26 US disclosed