Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHA2 | P29317 | 1/20 | 0.57 |
| ▸ | FLT4 | P35916 | 1/20 | 0.57 |
| ▸ | GSK3B | P49841 | 1/20 | 0.57 |
| ▸ | RARB | P10826 | 1/20 | 0.57 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 5/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 2/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | XBP1 | P17861 | 1/20 | 0.55 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.55 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.55 |
| ▸ | RELA | Q04206 | 1/20 | 0.55 |
| ▸ | DPP4 | P27487 | 6/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9147446 | 1.00 | EPHA2 (0.57) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9147028 | 0.90 | EPHA2 (0.71) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9147035 | 0.90 | EPHA2 (0.71) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL10512615 | 0.87 | KMT2A (0.56) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9045050 | 0.87 | KMT2A (0.56) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7005274 | 0.84 | EPHA2 (0.54) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7005284 | 0.84 | EPHA2 (0.54) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL7005262 | 0.84 | EPHA2 (0.54) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9537192 | 0.82 | EPHA2 (0.61) | EPHA2FLT4GSK3BRARBTBXAS1 | |
| SCHEMBL9144116 | 0.82 | DPP4 (0.47) | EPHA2FLT4GSK3BRARBTBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0388298-B1 | Derivatives of pyridone carboxylic acids substituted by an azetidine, their preparation and their use as medicines | ESTEVE LABOR DR (ES) | 1995-06-21 | — | — | EP | claimed |
| US-5393758-A | Bactericides, microbiocides | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1995-02-28 | — | — | US | claimed |
| US-5393758-A | Bactericides, microbiocides | LABORATORIOS DEL DR. ESTEVE S.A. (ES) | 1995-02-28 | — | — | US | disclosed |