Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MANBA | O00462 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 8/20 | 0.34 |
| ▸ | SLC5A1 | P13866 | 2/20 | 0.33 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL468525 | 0.79 | SLC5A2 (0.43) | MANBASLC5A2SLC5A1EPHX1 | |
| SCHEMBL13415299 | 0.79 | SLC5A2 (0.43) | MANBASLC5A2SLC5A1EPHX1 | |
| SCHEMBL16235720 | 0.79 | MANBA (0.43) | MANBALMNATHRBHIF1A | |
| SCHEMBL9809652 | 0.77 | SLC5A2 (0.43) | SLC5A2ALDH1A1 | |
| SCHEMBL20373569 | 0.76 | EPHX1 (0.34) | MANBALMNATHRBHIF1ASLC5A2 | |
| SCHEMBL4736780 | 0.70 | MEN1 (0.39) | EPHX1ALDH1A1 | |
| SCHEMBL2184757 | 0.70 | MEN1 (0.39) | EPHX1ALDH1A1 | |
| SCHEMBL7149420 | 0.70 | MEN1 (0.39) | EPHX1ALDH1A1 | |
| SCHEMBL12118236 | 0.70 | EPHX1 (0.35) | EPHX1 | |
| SCHEMBL12118232 | 0.70 | EPHX1 (0.35) | EPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0649443-A4 | OXAZOLONE DERIVED MATERIALS. | LEGOMER PARTNERS LP (US) | 1995-11-08 | — | — | EP | disclosed |
| CN-1105353-A | Modular design and synthesis of oxazolone-derived molecules | ARQULE PARTNERS L P (US) | 1995-07-19 | — | — | CN | disclosed |
| EP-0649443-A1 | OXAZOLONE DERIVED MATERIALS | LEGOMER PARTNERS, L.P. (US) | 1995-04-26 | — | — | EP | disclosed |