Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY5 | O95622 | 11/20 | 0.71 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.60 |
| ▸ | PI4KA | P42356 | 3/20 | 0.54 |
| ▸ | PI4K2B | Q8TCG2 | 3/20 | 0.54 |
| ▸ | PI4K2A | Q9BTU6 | 3/20 | 0.54 |
| ▸ | PI4KB | Q9UBF8 | 3/20 | 0.54 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.54 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.54 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | CHKA | P35790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9151388 | 0.86 | ADCY5 (0.64) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6045745 | 0.83 | ADCY5 (1.00) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6045813 | 0.83 | ADCY5 (1.00) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6045769 | 0.83 | ADCY5 (1.00) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6045770 | 0.83 | ADCY5 (1.00) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL9684255 | 0.82 | ADCY5 (0.72) | ADCY5ADORA2API4KAPI4K2BPI4K2A | |
| SCHEMBL6045754 | 0.81 | ADCY5 (1.00) | ADCY5ADORA2A | |
| SCHEMBL6045569 | 0.81 | ADCY5 (1.00) | ADCY5ADORA2A | |
| SCHEMBL6045626 | 0.81 | ADCY5 (1.00) | ADCY5ADORA2A | |
| SCHEMBL6045622 | 0.81 | ADCY5 (1.00) | ADCY5ADORA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0369409-B1 | Carbocyclic nucleosides and nucleotides | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1995-01-04 | — | — | EP | claimed |
| EP-0369409-A1 | Carbocyclic nucleosides and nucleotides | INSTITUTE OF ORGANIC CHEMISTRY AND BIOCHEMISTRY OF THE ACADEMY OF SCIENCES OF THE CZECH REPUBLIC (CS) | 1990-05-23 | — | — | EP | claimed |
| EP-0369409-B1 | Carbocyclic nucleosides and nucleotides | ACAD OF SCIENCE CZECH REPUBLIC (CS) | 1995-01-04 | — | — | EP | disclosed |