Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.45 |
| ▸ | PARP1 | P09874 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.44 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 8/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.42 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.42 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL914669 | 1.00 | SLC2A1 (0.45) | SLC2A1PARP1SCN1ASCN5ASCN9A | |
| SCHEMBL914823 | 0.89 | PARP1 (0.43) | PARP1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL914311 | 0.88 | PARP1 (0.43) | PARP1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL914473 | 0.88 | KMT2A (0.44) | PARP1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL914372 | 0.88 | PARP1 (0.43) | SLC2A1PARP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL914256 | 0.88 | KMT2A (0.44) | PARP1KDM4EALDH1A1CYP1A2CYP2D6 | |
| SCHEMBL914856 | 0.88 | KMT2A (0.43) | SLC2A1PARP1SCN1ASCN5ASCN9A | |
| SCHEMBL915767 | 0.88 | RHEB (0.53) | KDM4EALDH1A1KMT2A | |
| SCHEMBL913763 | 0.87 | KMT2A (0.46) | SLC2A1PARP1KDM4EALDH1A1CYP1A2 | |
| SCHEMBL913827 | 0.87 | KMT2A (0.46) | SLC2A1PARP1KDM4EALDH1A1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015180-A1 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015180-A1 | Chemokine receptor antagonists | ACKR3, CXCR2, CXCR4 | SLC2A1 820/4885PARP1 2933/4885SCN1A 2218/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.