SCHEMBL914867

SCHEMBL914867

CCO[Si](C)(CCCC#N)OCC

nearest known ligand 0.42

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19680572 0.90 TSHR (0.38) TSHR
SCHEMBL1995814 0.86 TSHR (0.35) TSHR
SCHEMBL2864681 0.83 TSHR (0.42) TSHR
SCHEMBL31338964 0.81 GAA (0.32) TSHR
SCHEMBL28831384 0.81
SCHEMBL1585427 0.80 TSHR (0.44) TSHR
SCHEMBL166002 0.80 TSHR (0.44) TSHR
SCHEMBL18138424 0.78
SCHEMBL30736006 0.78 TSHR (0.42) TSHR
SCHEMBL646411 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 220 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118197680-A Power cable 河北飞驰线缆有限公司 2024-06-14 CN claimed
EP-1448569-A1 PROCESS FOR PREPARING BIS(SILYLORGANO)AMINES General Electric Company (US) 2004-08-25 EP claimed
WO-2003044027-A1 PROCESS FOR PREPARING BIS(SILYLORGANO) AMINES GENERAL ELECTRIC COMPANY (US) 2003-05-30 WO claimed
US-6417381-B1 HYDROGENATION OF CYANOORGANOSILANE USING RHODIUM, RUTHENIUM, PALLADIUM, OR PLATINUM CATALYST CROMPTON CORPORATION 2002-07-09 US claimed
EP-3733756-B1 TREAD RUBBER COMPOSITION FOR STUDLESS WINTER TIRES SUMITOMO RUBBER IND (JP) 2026-01-28 EP disclosed
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-12-25 US disclosed
US-12410263-B2 Modified high-Cis polybutadiene polymer, related methods and rubber compositions BRIDGESTONE AMERICAS TIRE OPERATIONS, LLC (US) 2025-09-09 US disclosed
US-20250066516-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME BRIDGESTONE CORPORATION (JP) 2025-02-27 US disclosed
EP-4495146-A2 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS Bridgestone Americas Tire Operations, LLC (US) 2025-01-22 EP disclosed
EP-4457250-A1 HYDROGENATED POLYBUTADIENE POLYMERS AND RUBBER COMPOSITIONS INCORPORATING SAME Bridgestone Corporation (JP) 2024-11-06 EP disclosed
EP-3966259-B1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS BRIDGESTONE AMERICAS TIRE OPERATIONS LLC (US) 2024-10-30 EP disclosed
US-12109812-B2 Ink jet printing method and ink jet printing apparatus SEIKO EPSON CORPORATION (JP) 2024-10-08 US disclosed
US-4766181-A Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1988-08-23 US disclosed
US-4758637-A Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1988-07-19 US disclosed
EP-0269023-A2 Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1988-06-01 EP disclosed
EP-0214658-A2 Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1987-03-18 EP disclosed
US-4640962-A Silicone-modified polyester resin and silicone-sheathed polyester fibers made therefrom UNION CARBIDE CORPORATION (US) 1987-02-03 US disclosed
EP-0158140-A2 Olefin polymer compositions containing silicone additives and the use thereof in the production of film material UNION CARBIDE CORPORATION (US) 1985-10-16 EP disclosed
US-4535113-A IMPROVED MECHANICAL AND OPTICAL PROPERTIES UNION CARBIDE CORPORATION (US) 1985-08-13 US disclosed
US-4012403-A REDUCING B-CYANOETHYL-TRIALKOXYSILANE WITH SULFUR UNION CARBIDE CORPORATION (US) 1977-03-15 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250389555-A1 MODIFIED HIGH-CIS POLYBUTADIENE POLYMER, RELATED METHODS AND RUBBER COMPOSITIONS MALT1, INO80C, RTCB TSHR 1694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.