Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.47 |
| ▸ | LPAR3 | Q9UBY5 | 2/20 | 0.44 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1483633 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL11330627 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL11330989 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL31216108 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL11333125 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL3946408 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL11439202 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL11337846 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL11336970 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT | |
| SCHEMBL9149282 | 1.00 | TSHR (0.73) | TSHRALDH1A1MEN1THRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668259-A1 | A method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | MEDICEChem.-Pharm. Fabrik Pütter GmbH & Co. KG (DE) | 1995-08-23 | — | — | EP | disclosed |
| US-5434302-A | Method for the preparation of optically active 2-aryl alkyl aldehydes and formation of 2-aryl-alkanoic acids therefrom | PARADIES H HENRICH (DE) | 1995-07-18 | — | — | US | disclosed |