⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9385585 | 0.59 | — | — | |
| SCHEMBL28835013 | 0.48 | — | — | |
| SCHEMBL441039 | 0.47 | — | — | |
| SCHEMBL2679452 | 0.43 | — | — | |
| SCHEMBL20769115 | 0.41 | — | — | |
| SCHEMBL1904468 | 0.38 | — | — | |
| SCHEMBL5787030 | 0.38 | — | — | |
| SCHEMBL279754 | 0.37 | — | — | |
| Hydrochloric Acid SCHEMBL23214698 | 0.36 | — | — | |
| Formic Acid SCHEMBL31539653 | 0.36 | MAN1B1 (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0631581-A4 | INTERMEDIATES AND A PROCESS FOR SYNTHESIS OF TETRAHYDROPTERIDINE C6-STEREOISOMERS, INCLUDING (6S)-TETRAHYDROFOLATE AND N5-FORMYL-(6S)-TETRHYDROFOLATE. | BAILEY STEVENW (US) | 1995-08-02 | — | — | EP | disclosed |
| EP-0631581-A1 | INTERMEDIATES AND A PROCESS FOR SYNTHESIS OF TETRAHYDROPTERIDINE C6-STEREOISOMERS, INCLUDING (6S)-TETRAHYDROFOLATE AND N5-FORMYL-(6S)-TETRHYDROFOLATE | BAILEY, StevenW. (US) | 1995-01-04 | — | — | EP | disclosed |
| US-5350851-A | Intermediates and a process for synthesis of tetrahydropteridine C6-stereoisomers, including (6S)-tetrahydrofolate and N5-formyl-(6S)-tetrahydrofolate | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION (US) | 1994-09-27 | — | — | US | disclosed |
| WO-1993019069-A1 | INTERMEDIATES AND A PROCESS FOR SYNTHESIS OF TETRAHYDROPTERIDINE C6-STEREOISOMERS, INCLUDING (6S)-TETRAHYDROFOLATE AND N5-FORMYL-(6S)-TETRHYDROFOLATE | BAILEY STEVEN W (US) | 1993-09-30 | — | — | WO | disclosed |
| US-5198547-A | Process for N5-formylating tetrahydropteridines | SOUTH ALABAMA MEDICAL SCIENCE FOUNDATION, USA (US) | 1993-03-30 | — | — | US | disclosed |