Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RHEB | Q15382 | 1/20 | 0.37 |
| ▸ | MCHR1 | Q99705 | 3/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.35 |
| ▸ | MAOB | P27338 | 3/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | HTR7 | P34969 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.33 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6963768 | 1.00 | RHEB (0.37) | RHEBMCHR1CNR1KMT2ASOS1 | |
| SCHEMBL914177 | 1.00 | RHEB (0.37) | RHEBMCHR1CNR1KMT2ASOS1 | |
| SCHEMBL6964663 | 0.95 | RHEB (0.36) | RHEBMCHR1CNR1KMT2ASOS1 | |
| Hydrochloric Acid SCHEMBL914988 | 0.94 | RHEB (0.36) | RHEBMCHR1CNR1KMT2ASOS1 | |
| SCHEMBL915527 | 0.93 | MCHR1 (0.37) | MCHR1KMT2ASOS1ALDH1A1HTR7 | |
| SCHEMBL914780 | 0.93 | MCHR1 (0.37) | MCHR1KMT2ASOS1ALDH1A1HTR7 | |
| SCHEMBL6960183 | 0.93 | MCHR1 (0.37) | MCHR1KMT2ASOS1ALDH1A1HTR7 | |
| SCHEMBL6963420 | 0.93 | RHEB (0.38) | RHEBMCHR1CNR1KMT2ASOS1 | |
| Hydrochloric Acid SCHEMBL916205 | 0.92 | RHEB (0.38) | RHEBMCHR1CNR1KMT2ASOS1 | |
| SCHEMBL4406704 | 0.90 | SOS1 (0.34) | MCHR1CNR1SOS1MAOBMAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110015180-A1 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2011-01-20 | — | — | US | claimed |
| US-20110015180-A1 | Chemokine receptor antagonists | NOVARTIS AG (CH) | 2011-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110015180-A1 | Chemokine receptor antagonists | ACKR3, CXCR2, CXCR4 | RHEB 3019/4885MCHR1 257/4885CNR1 134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.