Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | PDE5A | O76074 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | RAB9A | P51151 | 5/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL91408 | 0.89 | PDE5A (0.74) | GAACYP1A2CYP2C19PDE5AALDH1A1 | |
| SCHEMBL93110 | 0.88 | PDE5A (0.76) | GAACYP1A2CYP2C19PDE5AALDH1A1 | |
| SCHEMBL9835391 | 0.88 | SMN1; SMN2 (0.68) | GAACYP1A2CYP2C19PDE5AALDH1A1 | |
| SCHEMBL10084854 | 0.85 | PDE5A (0.57) | GAACYP1A2CYP2C19PDE5AALDH1A1 | |
| SCHEMBL92485 | 0.85 | GAA (0.55) | GAACYP1A2CYP2C19PDE5AALDH1A1 | |
| SCHEMBL14350428 | 0.84 | KMT2A (0.58) | GAACYP1A2CYP2C19PDE5ASMN1; SMN2 | |
| SCHEMBL1846537 | 0.82 | CYP1A2 (0.68) | GAACYP1A2CYP2C19ALDH1A1RAB9A | |
| SCHEMBL10084284 | 0.82 | MEN1 (0.67) | CYP1A2CYP2C19PDE5AALDH1A1RAB9A | |
| SCHEMBL9232215 | 0.82 | GAA (1.00) | GAACYP1A2CYP2C19ALDH1A1SMN1; SMN2 | |
| SCHEMBL2612387 | 0.81 | SMN1; SMN2 (0.73) | ALDH1A1RAB9ANPC1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8129415-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-03-06 | — | — | US | disclosed |
| US-8119645-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-8119646-B2 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2012-02-21 | — | — | US | disclosed |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-11-26 | — | — | US | disclosed |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | BAYER CROPSCIENCE AG (DE) | 2009-10-15 | — | — | US | disclosed |
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | BAYER CROPSCIENCE AG (DE) | 2009-07-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090192196-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | GAA 677/4885CYP1A2 15/4885CYP2C19 51/4885 |
| US-20090258875-A1 | Fungicide Hydroximoyl-Tetrazole Derivatives | HAAO, CYP51A1, CYP8B1 | GAA 941/4885CYP1A2 15/4885CYP2C19 50/4885 |
| US-20090291969-A1 | Fungicide hydroximoyl-tetrazole derivatives | HAAO, HAO1, CYP51A1 | GAA 679/4885CYP1A2 17/4885CYP2C19 54/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.