⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8640368 | 0.93 | MLNR (0.55) | — | |
| SCHEMBL9147354 | 0.90 | — | — | |
| SCHEMBL9153067 | 0.89 | — | — | |
| SCHEMBL9150368 | 0.89 | — | — | |
| SCHEMBL9151105 | 0.89 | MLNR (0.61) | — | |
| SCHEMBL9146119 | 0.88 | — | — | |
| SCHEMBL9150629 | 0.88 | — | — | |
| SCHEMBL8638345 | 0.87 | KCNH2 (0.68) | — | |
| SCHEMBL8638021 | 0.87 | MLNR (0.59) | — | |
| SCHEMBL9371607 | 0.87 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5457115-A | Treating anxiety, depression, sleep disorders, migranes, schizophrenia or Parkinson's disease in humans | H. LUNDBECK A/S (DK) | 1995-10-10 | — | — | US | disclosed |
| US-5322851-A | Indole derivatives | H. LUNDBECK A/S (DK) | 1994-06-21 | — | — | US | disclosed |
| US-5216001-A | Central nervous system disorders | H. LUNBECK A/S (DK) | 1993-06-01 | — | — | US | disclosed |
| EP-0465398-A2 | Novel indole derivatives | H. LUNDBECK A/S (DK) | 1992-01-08 | — | — | EP | disclosed |