Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5634310 | 0.71 | PDE10A (0.45) | PDE10AKDM4EALDH1A1MAP4K4 | |
| SCHEMBL9378584 | 0.67 | KDM4E (0.42) | PDE10AKDM4EALDH1A1MAP4K4 | |
| SCHEMBL9936182 | 0.67 | PDE10A (0.46) | PDE10AKDM4EALDH1A1MAP4K4 | |
| SCHEMBL13934564 | 0.67 | PDE10A (0.41) | PDE10AKDM4EALDH1A1MAP4K4 | |
| SCHEMBL22755250 | 0.67 | PDE10A (0.41) | PDE10AKDM4EALDH1A1MAP4K4 | |
| Hydrochloric Acid SCHEMBL31728514 | 0.66 | PDE10A (0.40) | PDE10AKDM4EALDH1A1MAP4K4 | |
| SCHEMBL22109267 | 0.61 | KDM4E (0.38) | PDE10AKDM4EALDH1A1 | |
| SCHEMBL8129636 | 0.61 | KDM4E (0.44) | PDE10AKDM4EALDH1A1 | |
| SCHEMBL16746131 | 0.55 | IRAK4 (0.39) | KDM4EALDH1A1MAP4K4 | |
| SCHEMBL1369725 | 0.53 | NPC1 (0.37) | PDE10AKDM4EALDH1A1MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5439904-A | Enzyme inhibitors of human leukocyte elastase; respiratory system disorders; antiarthritic agents | SYNPHAR LABORATORIES, INC. (CA) | 1995-08-08 | — | — | US | disclosed |