⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9214201 | 0.88 | — | — | |
| SCHEMBL9207020 | 0.88 | — | — | |
| SCHEMBL9215474 | 0.85 | USP2 (0.33) | — | |
| SCHEMBL187063 | 0.78 | — | — | |
| SCHEMBL18134202 | 0.78 | — | — | |
| SCHEMBL3659642 | 0.78 | — | — | |
| SCHEMBL109050 | 0.78 | EPHX1 (0.35) | — | |
| SCHEMBL12462586 | 0.78 | — | — | |
| SCHEMBL231498 | 0.73 | — | — | |
| SCHEMBL25257366 | 0.72 | EPHX1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12583818-B2 | Compound, preparation method thereof, and use thereof | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2026-03-24 | — | — | US | disclosed |
| WO-2025044897-A1 | CYCLIC 2-AMINOPYRIMIDINE COMPOUND AND PHARMACEUTICAL COMPOSITION AND USE THEREOF | 中国科学院上海有机化学研究所 | 2025-03-06 | — | — | WO | disclosed |
| EP-4065553-B1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU GYEONGBUK MEDICAL INNOVATION FOUND (KR) | 2025-01-29 | — | — | EP | disclosed |
| CN-114981241-B | Novel compounds, process for their preparation and their use | 大邱庆北尖端医疗产业振兴财团 | 2024-11-19 | — | — | CN | disclosed |
| CN-117865848-A | Preparation method of montelukast sodium side chain acid key intermediate | 艾美科健（中国）生物医药有限公司 | 2024-04-12 | — | — | CN | disclosed |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| US-20230142654-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | PIMEDBIO, INC. (KR) | 2023-05-11 | — | — | US | disclosed |
| EP-4065553-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | Daegu-Gyeongbuk Medical Innovation Foundation (KR) | 2022-10-05 | — | — | EP | disclosed |
| CN-114981241-A | Novel compound, preparation method and application thereof | 大邱庆北尖端医疗产业振兴财团 | 2022-08-30 | — | — | CN | disclosed |
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |
| WO-2021145729-A1 | NOVEL COMPOUND, PREPARATION METHOD THEREOF, AND USE THEREOF | DAEGU-GYEONGBUK MEDICAL INNOVATION FOUNDATION (KR) | 2021-07-22 | — | — | WO | disclosed |
| CN-103058884-B | Method for synthesizing 1-hydroxymethyl cyclopropyl acetonitrile | WUHAN SAITHCHEM. CO., LIMITED (CN) | 2014-10-29 | — | — | CN | disclosed |
| CN-103058884-A | Method for synthesizing 1-hydroxymethyl cyclopropyl acetonitrile | WUHAN SAITHCHEM CO LTD | 2013-04-24 | — | — | CN | disclosed |
| US-5416231-A | Prostaglandin I2 derivatives | ASAHI GLASS COMPANY, LTD. (JP) | 1995-05-16 | — | — | US | disclosed |
| EP-0553352-B1 | NOVEL PROSTAGLANDIN I2 DERIVATIVES | ASAHI GLASS CO LTD (JP) | 1995-03-15 | — | — | EP | disclosed |
| EP-0553352-A1 | NOVEL PROSTAGLANDIN I2 DERIVATIVES | ASAHI GLASS COMPANY LTD. (JP) | 1993-08-04 | — | — | EP | disclosed |
| WO-1992004339-A1 | NOVEL PROSTAGLANDIN I2 DERIVATIVES | ASAHI GLASS COMPANY LTD. (JP) | 1992-03-19 | — | — | WO | disclosed |
| EP-0060077-A1 | Beta-lactam antibiotics, their preparation and use | BEECHAM GROUP PLC (GB) | 1982-09-15 | — | — | EP | disclosed |