SCHEMBL9150541

SCHEMBL9150541

CC1(C)CC(NC(=O)CCC(=O)NNC(=O)C(=O)NC2CC(C)(C)NC(C)(C)C2)CC(C)(C)N1

nearest known ligand 0.57

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.57
HTT P42858 2/20 0.47
POLB P06746 3/20 0.46
KMT2A Q03164 2/20 0.46
RECQL P46063 2/20 0.46
MEN1 O00255 1/20 0.46
MAPT P10636 1/20 0.46
KDM4E B2RXH2 1/20 0.46
USP2 O75604 1/20 0.43
PKM P14618 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9149688 0.90 GAA (0.49) GAAHTTPOLBKMT2ARECQL
SCHEMBL9154493 0.87 GAA (0.47) GAAHTTPOLBKMT2ARECQL
SCHEMBL9154314 0.87 GAA (0.52) GAAHTTPOLBKMT2ARECQL
SCHEMBL2901212 0.87 GAA (0.71) GAAHTTPOLBKMT2ARECQL
SCHEMBL9150456 0.86 GAA (0.48) GAAHTTPOLBKMT2ARECQL
SCHEMBL9152963 0.86 GAA (0.46) GAAHTTPOLBKMT2ARECQL
SCHEMBL9151526 0.85 GAA (0.45) GAAHTTPOLBKMT2ARECQL
SCHEMBL9158345 0.85 GAA (0.45) GAAHTTPOLBKMT2ARECQL
SCHEMBL9153064 0.85 GAA (0.45) GAAHTTPOLBKMT2ARECQL
SCHEMBL9151499 0.82 GAA (0.46) GAAHTTPOLBKMT2ARECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5397821-A Light and heat stabilizers, low volatility ELFATOCHEM NORTH AMERICA, INC. (US) 1995-03-14 US disclosed
US-5338853-A N-(2,2,6,6-tetraalkyl-4-piperidinyl)amic acid hydrazides; contain light stabilizing group and heat stabilizing group ELF ATOCHEM NORTH AMERICA, INC. (US) 1994-08-16 US disclosed
EP-0434080-A1 Derivatives of N-hals-substituted amic acid hydrazides ELF ATOCHEM NORTH AMERICA, INC. (US) 1991-06-26 EP disclosed