SCHEMBL9150644

SCHEMBL9150644

CCCCc1cc(S)ccc1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TYR P14679 3/20 0.52
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
HTT P42858 2/20 0.44
ALOX5 P09917 2/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
MAPT P10636 1/20 0.44
ALOX15 P16050 1/20 0.44
TSHR P16473 1/20 0.44
TDP1 Q9NUW8 1/20 0.44
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
HPGD P15428 2/20 0.41
MAPK1 P28482 2/20 0.41
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
IAPP P10997 1/20 0.40
ELANE P08246 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9006698 0.85 TYR (0.67) TYRMEN1KMT2AHTTALOX5
SCHEMBL27684553 0.83 AKR1B1 (0.42) TYRMEN1KMT2AHTTALOX5
SCHEMBL30708512 0.80 TYR (0.55) TYRMEN1KMT2AHTTALOX5
SCHEMBL30223636 0.80 TYR (0.71) TYRMEN1KMT2AHTTALOX5
SCHEMBL26849 0.80 TYR (0.71) TYRMEN1KMT2AHTTALOX5
SCHEMBL17709428 0.80 TYR (0.55) TYRMEN1KMT2AHTTALOX5
SCHEMBL1970437 0.80 TYR (0.41) TYRMEN1KMT2AHTTALOX5
SCHEMBL1275210 0.79 ESR1 (0.53) MEN1KMT2AHTTCYP3A4MAPT
SCHEMBL21908 0.78 TYR (0.53) TYRMEN1KMT2AHTTALOX5
SCHEMBL30281405 0.78 TYR (0.53) TYRMEN1KMT2AHTTALOX5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106591547-B A kind of quenching oil compound and its manufacturing method 中国石油化工股份有限公司 2018-07-31 CN disclosed
CN-106590767-B A kind of biodiesel composition and its manufacturing method 中国石油化工股份有限公司 2018-05-18 CN disclosed
CN-105566720-A Polymer composition and application thereof CHINA PETROLEUM & CHEM CORP 2016-05-11 CN disclosed
CN-105315183-A Screen phenol compound and its manufacturing method and use as anti-oxidant CHINA PETROLEUM & CHEMICAL 2016-02-10 CN disclosed
CN-105218420-A A kind ofly shield phenolic compound, its manufacture method and the application as oxidation inhibitor thereof CHINA PETROLEUM & CHEMICAL 2016-01-06 CN disclosed
CN-105130859-A Screen phenol compound, manufacturing method and application thereof as antioxidant CHINA PETROLEUM & CHEMICAL 2015-12-09 CN disclosed
WO-2012135669-A1 NITROGEN RING CONTAINING COMPOUNDS FOR TREATMENT OF INFLAMMATORY DISORDERS WEINGARTEN M DAVID (US) 2012-10-04 WO disclosed
CN-1168693-C Substituted phenols and thiophenols as antioxidants ���µ�˹ҩ�﹫˾ 2004-09-29 CN disclosed
CN-1147495-C Alkyl-4-silyl heterocyclic phenols and thiophenols as antioxidants ���µ�˹ҩ�﹫˾ 2004-04-28 CN disclosed
CN-1261367-A Alkyl-4-silylheterocyclic phenols and thiophenols as antioxidant agents HOECHST MARION ROUSSEL INC (US) 2000-07-26 CN disclosed
CN-1237955-A Substituted phenols and thiophenols as antioxidants HOECHST MARION ROUSSEL INC (US) 1999-12-08 CN disclosed
CN-1216993-A alkyl-4-silyl-phenols and esters thereof as antiatherosclerotic agents HOECHST MARION ROUSSEL INC (US) 1999-05-19 CN disclosed
EP-0410305-B1 Use of bis(4-hydroxyphenylthio) methane derivatives in treating diabetes mellitus MERRELL DOW PHARMA (US) 1995-02-15 EP disclosed
EP-0410305-A2 Use of bis(4-hydroxyphenylthio) methane derivatives in treating diabetes mellitus MERRELL DOW PHARMACEUTICALS INC. (US) 1991-01-30 EP disclosed
EP-0382213-A2 Biphenyl derivative, nerve cell degeneration repairing or protecting agent and process for preparing a phenyl derivative contained in the agent OTSUKA PHARMACEUTICAL CO., LTD. (JP) 1990-08-16 EP disclosed
US-RE32618-E ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1988-03-01 US disclosed
EP-0137395-A2 4-(Hydroxyphenylthio)-benzoates CIBA-GEIGY AG (CH) 1985-04-17 EP disclosed
US-4308199-A ANTIOXIDANTS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1981-12-29 US disclosed
US-4108831-A FOR CONJUGATED DIENE POLYMERS THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-08-22 US disclosed