Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.41 |
| ▸ | ASPH | Q12797 | 2/20 | 0.41 |
| ▸ | KDM8 | Q8N371 | 2/20 | 0.41 |
| ▸ | ALB | P02768 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | GSK3A | P49840 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 2/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 2/20 | 0.32 |
| ▸ | CA9 | Q16790 | 2/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | CA3 | P07451 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | SELL | P14151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27531532 | 0.82 | CYP3A4 (0.34) | KDM4EASPHKDM8HPGDKMT2A | |
| SCHEMBL31574400 | 0.75 | DPP4 (0.52) | KDM4EDPP4HSD17B10ALDH1A1MAPK1 | |
| SCHEMBL10760359 | 0.73 | DPP4 (0.41) | KDM4EASPHKDM8DPP4HSD17B10 | |
| SCHEMBL10765922 | 0.71 | KDM4E (0.46) | KDM4EASPHKDM8ALBDPP4 | |
| SCHEMBL21262024 | 0.69 | ALB (0.50) | KDM4EALBDPP4CA12CA1 | |
| SCHEMBL3520296 | 0.68 | EGLN3 (0.37) | KDM4EASPHKDM8ALBDPP4 | |
| SCHEMBL3105391 | 0.68 | KDM4E (0.42) | KDM4EASPHKDM8GSK3AGSK3B | |
| SCHEMBL10465944 | 0.68 | KDM4E (0.42) | KDM4EASPHKDM8GSK3AGSK3B | |
| Hydrochloric Acid SCHEMBL9651745 | 0.67 | KDM4E (0.41) | KDM4EASPHKDM8CA1CA2 | |
| SCHEMBL10766033 | 0.67 | DPP4 (0.42) | KDM4EDPP4CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0655998-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 2,6-DICHLORO-5-FLUORONICOTINIC ACID AND 2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE. | WARNER LAMBERT CO (US) | 1995-06-07 | — | — | EP | claimed |
| WO-1994004501-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 2,6-DICHLORO-5-FLUORONICOTINIC ACID AND 2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | claimed |
| EP-0655998-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 2,6-DICHLORO-5-FLUORONICOTINIC ACID AND 2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE. | WARNER LAMBERT CO (US) | 1995-06-07 | — | — | EP | disclosed |
| WO-1994004501-A1 | IMPROVED PROCESS FOR THE SYNTHESIS OF 2,6-DICHLORO-5-FLUORONICOTINIC ACID AND 2,6-DICHLORO-5-FLUORONICOTINOYL CHLORIDE | WARNER-LAMBERT COMPANY (US) | 1994-03-03 | — | — | WO | disclosed |