Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | CES2 | O00748 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | PLA2G2C | Q5R387 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8169403 | 1.00 | CES1 (0.47) | CES1CES2MEN1THRBHTT | |
| SCHEMBL9147628 | 0.80 | CES1 (0.44) | CES1CES2MEN1THRBHTT | |
| SCHEMBL9147609 | 0.80 | CES1 (0.44) | CES1CES2MEN1THRBHTT | |
| SCHEMBL12039682 | 0.69 | — | — | |
| SCHEMBL17830660 | 0.67 | CES1 (0.59) | CES1CES2MEN1THRBHTT | |
| SCHEMBL976124 | 0.66 | — | — | |
| SCHEMBL30988988 | 0.66 | — | — | |
| SCHEMBL17830580 | 0.65 | MEN1 (0.67) | CES1CES2MEN1THRBHTT | |
| SCHEMBL30916095 | 0.65 | — | — | |
| SCHEMBL4364045 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0532577-B1 | FUNCTIONALIZED TRIFLUOROVINYL ETHERS AND POLYMERS THEREFROM | DU PONT (US) | 1995-01-11 | — | — | EP | claimed |
| EP-0532577-B1 | FUNCTIONALIZED TRIFLUOROVINYL ETHERS AND POLYMERS THEREFROM | DU PONT (US) | 1995-01-11 | — | — | EP | disclosed |
| US-5237026-A | Functionalized trifluorovinyl ethers and polymers therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-08-17 | — | — | US | disclosed |
| US-5196569-A | Functionalized trifluorovinyl ethers and polymers therefrom | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-23 | — | — | US | disclosed |
| WO-1991018859-A1 | FUNCTIONALIZED TRIFLUOROVINYL ETHERS AND POLYMERS THEREFROM | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1991-12-12 | — | — | WO | disclosed |