Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | CNR2 | P34972 | 2/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | PTGES | O14684 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9152074 | 0.88 | MAOB (0.42) | TSHRMAOBALDH1A1MAPK1TDP1 | |
| SCHEMBL30167692 | 0.77 | TSHR (0.54) | TSHRMAOBCYP1A2CYP19A1CYP2C9 | |
| SCHEMBL255565 | 0.77 | TSHR (0.54) | TSHRMAOBCYP1A2CYP19A1CYP2C9 | |
| SCHEMBL10477053 | 0.75 | TSHR (0.62) | TSHRCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL1521996 | 0.74 | TSHR (0.65) | TSHRCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL9149380 | 0.74 | TSHR (0.65) | TSHRCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL4663093 | 0.74 | TSHR (0.65) | TSHRCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL1522035 | 0.74 | TSHR (0.65) | TSHRCYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL255563 | 0.72 | KMT2A (0.54) | TSHRMAOBKMT2A | |
| SCHEMBL13272535 | 0.72 | KDM4E (0.60) | TSHRCYP1A2CYP2C9CYP2C19PTGES |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5397504-A | Liquid crystal | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1995-03-14 | — | — | US | disclosed |
| EP-0315701-B1 | BIPHENYL COMPOUND | KANTO KAGAKU (JP) | 1993-12-29 | — | — | EP | disclosed |
| EP-0315701-A1 | BIPHENYL COMPOUND | KANTO KAGAKU KABUSHIKI KAISHA (JP) | 1989-05-17 | — | — | EP | disclosed |