SCHEMBL9153155

SCHEMBL9153155

CCC[C@H]1CC[C@H](c2ccc(CC[C@H]3CC[C@H]([C@H]4CC[C@H](CCC)CC4)CC3)cc2)CC1

nearest known ligand 0.54

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.54
ALDH1A1 P00352 1/20 0.51
LMNA P02545 1/20 0.51
MAPT P10636 1/20 0.51
MEN1 O00255 1/20 0.51
MAPK1 P28482 1/20 0.51
KMT2A Q03164 1/20 0.51
SPHK1 Q9NYA1 12/20 0.48
ESR2 Q92731 1/20 0.42
SPHK2 Q9NRA0 7/20 0.42
MAOA P21397 1/20 0.41
MAOB P27338 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9853706 1.00 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9156298 1.00 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL9156308 1.00 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10718179 0.95 CYP2C9 (0.50) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10715665 0.95 CYP2C9 (0.50) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10553204 0.95 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10553199 0.95 CYP2C9 (0.58) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10718093 0.94 SPHK1 (0.50) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL10717179 0.94 SPHK1 (0.50) CYP2C9ALDH1A1LMNAMAPTMEN1
SCHEMBL7576264 0.94 CYP2C9 (0.54) CYP2C9ALDH1A1LMNAMAPTMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0445274-B1 LIQUID CRYSTALLINE MEDIUM MERCK PATENT GMBH (DE) 1995-01-18 EP disclosed
EP-0445274-A1 LIQUID CRYSTALLINE MEDIUM. MERCK PATENT GMBH (DE) 1991-09-11 EP disclosed
WO-1991002779-A1 LIQUID CRYSTALLINE MEDIUM MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1991-03-07 WO disclosed
EP-0125563-B1 BICYCLOHEXYL ETHANES MERCK PATENT GmbH (DE) 1987-05-27 EP disclosed
EP-0125563-A2 Bicyclohexyl ethanes MERCK PATENT GmbH (DE) 1984-11-21 EP disclosed