Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25543838 | 0.77 | SMN1; SMN2 (0.35) | SMN1; SMN2HPGDMEN1TSHRKMT2A | |
| SCHEMBL1838790 | 0.75 | SMN1; SMN2 (0.47) | SMN1; SMN2HPGDMEN1TSHRKMT2A | |
| SCHEMBL10175762 | 0.75 | SMN1; SMN2 (0.33) | SMN1; SMN2 | |
| SCHEMBL11269945 | 0.75 | HSD17B10 (0.38) | TSHRMAPK1 | |
| SCHEMBL2703 | 0.75 | — | — | |
| SCHEMBL1416856 | 0.75 | — | — | |
| SCHEMBL1416868 | 0.75 | — | — | |
| SCHEMBL15028888 | 0.75 | — | — | |
| SCHEMBL9149444 | 0.73 | — | — | |
| SCHEMBL9150885 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351782-B1 | Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition | HITACHI LTD (JP) | 1995-01-04 | — | — | EP | disclosed |
| US-5328643-A | Electrooptic display, switches, modulators; physical and chemical stability and spontaneous polarization | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-07-12 | — | — | US | disclosed |
| EP-0351782-A2 | Optically active compounds liquid crystal composition containing said compound, and liquid crystal optical modulator using said composition | HITACHI, LTD. (JP) | 1990-01-24 | — | — | EP | disclosed |