Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PNP | P00491 | 1/20 | 0.64 |
| ▸ | LMNA | P02545 | 1/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | HTT | P42858 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.64 |
| ▸ | NT5E | P21589 | 1/20 | 0.55 |
| ▸ | AHCY | P23526 | 2/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.49 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | HBB | P68871 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.46 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9153413 | 1.00 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL6839500 | 0.91 | PNP (0.64) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL23982120 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL21562191 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL5982387 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL12123492 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL8712178 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL1678967 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL176347 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D | |
| SCHEMBL29383092 | 0.89 | PNP (0.79) | PNPLMNATP53HTTPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5449664-A | Nucleosides | SYNTEX (U.S.A.) INC. (US) | 1995-09-12 | — | — | US | disclosed |
| EP-0457326-A1 | Antiviral agents | SYNTEX (U.S.A.) INC. (US) | 1991-11-21 | — | — | EP | disclosed |