Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | HTR2A | P28223 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | DRD3 | P35462 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.36 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.36 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.36 |
| ▸ | FFAR3 | O14843 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11554076 | 1.00 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL157028 | 0.97 | — | — | |
| SCHEMBL21519882 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL487120 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL487333 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL3182058 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL1157667 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL21219177 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL21225948 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A | |
| SCHEMBL767059 | 0.94 | TDP1 (0.38) | TDP1CHRM1AKR1A1CHRM3HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5432153-A | Iron compound; ketone; liquid; polyacrylamide or a copolymer or terpolymer of acrylamide with N-vinyl-2-pyrrolidone and/or sodium 2-acrylamide-2-methylpropanesulfonate. In gelling composition polymer is partly hydrolyzed. | PHILLIPS PETROLEUM COMPANY (US) | 1995-07-11 | — | — | US | claimed |
| US-5358043-A | Injecting for well bore treatment: an acrylamide-containing water-soluble polymer, an iron compound, a ketone compound and a liquid | PHILLIPS PETROLEUM COMPANY (US) | 1994-10-25 | — | — | US | claimed |