Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 13/20 | 0.61 |
| ▸ | NPC1 | O15118 | 5/20 | 0.61 |
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | RAB9A | P51151 | 4/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.61 |
| ▸ | L3MBTL1 | Q9Y468 | 9/20 | 0.56 |
| ▸ | BRD4 | O60885 | 1/20 | 0.56 |
| ▸ | MITF | O75030 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.52 |
| ▸ | TP53 | P04637 | 2/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031376 | 0.85 | KDM4E (0.60) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL27836693 | 0.80 | KDM4E (0.65) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL8030827 | 0.79 | KDM4E (0.63) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL4468901 | 0.77 | KDM4E (1.00) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL114710 | 0.75 | KDM4E (0.74) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL14768490 | 0.74 | KDM4E (0.79) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL30345672 | 0.74 | KDM4E (0.79) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL13415788 | 0.74 | KDM4E (0.72) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL28976997 | 0.73 | KDM4E (0.77) | KDM4ENPC1HTTRAB9AALOX12 | |
| SCHEMBL17799263 | 0.73 | KDM4E (0.71) | KDM4ENPC1HTTRAB9AALOX12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0376460-B1 | Liquid electrophotographic toner | MINNESOTA MINING & MFG (US) | 1995-02-22 | — | — | EP | disclosed |
| EP-0376460-A1 | Liquid electrophotographic toner | MINNESOTA MINING AND MANUFACTURING COMPANY (US) | 1990-07-04 | — | — | EP | disclosed |